Influence of Growth Factors on
Cell Division
Development, differentiation, and the maintenance
of vital functions require exact regulation
of the time and location of cell divisions.
Rapidly multiplying cells in embryonic tissues
must be controlled, just like those in stationary
phases in adult tissues. Rapid response to injury
or to foreign antigens requires controlled cell
division. Multicellular organisms have an extensive
repertoire of genetically regulated
mechanisms at their disposal for controlling
cell division and tissue proliferation. As a group,
they are referred to as growth factors. Every
growth factor has a specific cell surface receptor.
Binding to the receptor initiates (or in some
cases blocks) cell division. Most growth factors
regulate only certain types of cells and tissues.
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